Vision Realized – The Allergenex® Detection System. Now for the first time…
- It’s possible to provide a clinician with a comprehensive profiles test for 28 common food allergens, 40 common inhalant allergens, or 68 combined food & inhalant allergens…from a single spot of dried blood.
- The power of the microarray technology does not require the enzymatic enhancement of the protein IgE-allergen binding signal. Therefore, it is possible to detect and measure the actual amount of IgE binding, resulting in a true report of allergic sensitivity.
- By running all allergens simultaneously in triplicate, including positive and negative controls, well-to-well variability is eliminated. This further enables highly precise quantification of the relative sensitivity to each of the allergens. In effect, it is a personalized heat map of allergic sensitivity.
How it works…
Advantages of Allergenex® vs. ELISA
Convenience of blood collection
Using the lab’s proprietary blood collection kit in the clinician’s office, four spots of blood are collected from a simple finger stick. The need to draw several tubes of blood from the arm is eliminated.
Collection of the blood sample in the clinician’s office assures 100% patient compliance. No separate appointment and/or visit to the lab for blood collection by a phlebotomist is necessary.
Simultaneous testing of 28 common food allergens, 40 common inhalant allergens or 68 combined food & inhalant allergens and Total IgE in triplicate with controls eliminates the well-to-well variability associated with ELISA testing.
Speed to Report:
Enhanced kinetics of the biochip accelerates binding and the speed of test processing, resulting in efficient workflow and turnaround times superior to ELISA systems.
Each patient sample is tested for all allergens simultaneously in triplicate, with positive and negative controls, for unsurpassed precision and accuracy. Each sample includes Total IgE and 28 common food allergens, 40 common inhalant allergens or 68 combined food & inhalant allergens. The dramatic test redundancy of the microarray platform enables high sensitivity and specificity values that are >90%.
Positive/Negative Predictive Values:
The high specificity and sensitivity of the microarray combined with 28 common food allergens, 40 common inhalant allergens or 68 combined food & inhalant allergens and Total IgE delivers superior positive/negative predictive values to clinicians as compared to smaller regional profiles performed with ELISA systems.
Allergen concentration and purity standardization coupled with advanced microarray technology provide high precision and consistent results.
All microarrays are calibrated and quantified for excellent dependability.
Comparisons to skin testing and other ELISA methods demonstrate agreement in clinical indications.
Microarray manufacturing is performed in Class 1 clean rooms using advanced equipment and industry standardized operating procedures.
Purified and standardized allergen extracts are utilized in the microarray manufacturing process to assure consistent and repeatable results.
In summary, ease of blood collection, improved patient compliance, an expanded allergen profile and Total IgE with strong predictive values provide significant advantages to both clinicians and patients over current ELISA methods.
Your staff will love the simplicity.
You will love the profitability.